To delete vxfiVspCacheFile_0.tmp files created in windows while backing up open files.

This technote from Symantec is helpful.

http://seer.entsupport.symantec.com/docs/270127.htm

This technote uses a third party tool

http://www.sysinternals.com/ntw2k/freeware/procexp.shtml

for deleting the file.

The other way to remove this file is to reboot the server. We have had cache files upto 23 GB i a drive virtually threatenning to crash the application.